4 Reasons to Choose Nutravision for Macular Health & Vision Support

The macula makes up less than 2% of your retina, yet it is responsible for over 90% of the detail in everything you see, from reading small print to recognising faces. It is also one of the most energy-demanding tissues in the body, burning through oxygen faster than nearly any other organ except the brain.

That high demand comes at a cost. The macula is highly vulnerable to oxidative stress and ageing, and once its cells are damaged, the loss of central vision can be permanent. Macular degeneration already affects tens of millions worldwide and is the second most common cause of irreversible blindness, with incidence rising as lifespans lengthen and screen exposure grows.

That is why many people turn to supplements to support their macula and vision. The most popular are those containing lutein and zeaxanthin, based on the landmark AREDS2 Study. These macular carotenoids act as natural filters against blue light and oxidative stress, and they have become the foundation of many eye-health formulas.

But while lutein and zeaxanthin are essential antioxidants, their protection is only partial. They filter blue light and neutralise oxidative stress within the macula, yet deeper oxidative damage and reduced blood flow can still occur, especially with age. These are gaps that most standard formulas leave open.

This means there is more we can do to support macular health, and more nutrients are needed than lutein, zeaxanthin, or the AREDS2 formula alone.

The NP-10 System™

This is where the NP-10 System™ and Nutravision come in. Originally developed for glaucoma neuroprotection, Nutravision was built on the NP-10 System™ to support circulation, cellular energy, and optic nerve's resilience against stress. 

The NP-10 System™ and the 4 core areas that are vital for vision longevity

It soon became clear that the same pathways supporting the optic nerve also play a crucial role in maintaining the macula’s oxygen supply, nutrient flow, resistance to oxidative damage, and cell resilience.

This is where Nutravision excels: it protects the macula from multiple angles — supporting blood flow, deep antioxidant defence, and cell resilience — something that lutein or AREDS2 is not able to do.

Here are four reasons Nutravision stands apart, plus a bonus reason that many eye supplements overlook.

Reason 1: Triple Carotenoid Protection

Most macular supplements include just two carotenoids, lutein and zeaxanthin, which are essential for filtering blue light and protecting the macula from oxidative stress.
Nutravision goes one step further by adding a third carotenoid: crocin, the active compound from saffron.

These three nutrients work together to strengthen the macula’s natural defence system, helping the eyes filter light efficiently, maintain contrast sensitivity, and recover more easily from visual strain.

In an Australian open-label clinical trial of 93 adults with early to moderate macular degeneration, participants who took oral saffron for 12 months showed significant improvements in retinal response even when already using AREDS-style supplements. No saffron-related adverse effects were reported, suggesting it is both effective and well tolerated as a complementary approach to standard macular support.

Nutravision includes saffron precisely for this reason:  to enhance the protective effects of lutein and zeaxanthin on the macula.

“Saffron supplementation induces macular function improvements from baseline that are extended over a long-term follow up.” Dr. Marco Piccardi, Evidence-Based Complementary & Alternative Medicine, 2012

Reason 2: Zinc-Free

Unlike standard AREDS-style macular formulations that use zinc, Nutravision is deliberately zinc-free. Research published in Ophthalmology found that zinc can have variable genetic effects, meaning that it is potentially harmful for around 15% who carry certain genes. Scientists found that in these individuals, excess zinc intake may actually worsen macular health.

By omitting zinc, Nutravision offers a safer and more universally suitable option for long-term macular support. For most people, it’s best to obtain zinc naturally through a balanced diet rather than through high-dose supplementation.

Reason 3: Antioxidant Power x5

Most AREDS2 formulations and vision supplements rely on general antioxidants like vitamin C or vitamin E.

Nutravision goes far beyond that. The formula features five powerhouse antioxidants that deliver up to 50× greater antioxidant activity than vitamin C and act where ordinary antioxidants can’t: inside the cell’s mitochondria. This means protection not just at the surface, but at the very source of energy production, where oxidative stress begins.

Together, lutein and zeaxanthin, bilberry, grape seed, saffron, and ginkgo biloba form a complete antioxidant network that helps:

• Neutralise oxidative damage from light and daily stress
• Support healthy circulation to the macula and retina
• Energise the cells responsible for clear, lasting vision

By acting at the source of oxidative stress, Nutravision helps maintain the macula’s natural resilience, protecting long-term vision and supporting visual performance.

Reason 4: Ocular Circulation Support

Healthy circulation is what keeps the eyes nourished, oxygenated, and comfortable. The macula depends on a steady flow of blood through microscopic vessels to deliver nutrients and remove waste material. The problem is that circulation naturally declines with age and oxidative stress.

Nutravision promotes ocular blood flow through two key ingredients: ginkgo biloba and bilberry. Each are well-known for supporting microvascular function and capillary health. Together, they help ensure that oxygen and nutrients reach the macula efficiently, sustaining its high energy demands throughout the day.

In a German double-blind study, 99 patients with dry macular degeneration were treated with ginkgo biloba over a six-month period. The results showed a statistically significant improvement in visual acuity in the treatment group compared to placebo, highlighting ginkgo’s potential to support macular health through enhanced ocular blood flow and nutrient delivery.

“The study results show that Ginkgo biloba is not only safe but also clinically effective in age-related macular degeneration.” Dr. Angelika Dienel, Wiener Medizinische Wochenschrift, 2002

Bonus Reason 5: Homocysteine Metabolism

Elevated homocysteine, a naturally occurring amino acid linked to oxidative stress and impaired circulation, is still an under-recognised risk factor for macula and optic-nerve health. When homocysteine levels rise, blood vessels become less flexible, oxygen delivery declines, and oxidative damage increases. All of these place additional stress on the macula and surrounding retinal tissues.

A systematic review and meta-analysis of 11 studies (over 2,000 participants) found that people with macular degeneration had significantly higher homocysteine levels and lower vitamin B12 concentrations than healthy controls. Likewise, the Blue Mountains Eye Study showed that elevated homocysteine levels predicted a higher 10-year incidence of macular degeneration; each standard-deviation increase in homocysteine was linked to a 33% rise in AMD risk.

And finally, in the Women’s Antioxidant and Folic Acid Cardiovascular Study, daily supplementation with folic acid, vitamin B12 (and pyridoxine, vitamin B6) over 7 years reduced the risk of developing macular degeneration by 34% compared with placebo.

Nutravision helps to reduce homocysteine levels through its methylated B-vitamin pair, methylcobalamin (B12) and methylfolate (B9), key nutrients for homocysteine metabolism, cell repair and vascular integrity. In addition, nicotinamide (B3) and vitamin D3 complement this process by supporting mitochondrial energy and cell repair. 

Through promoting balanced homocysteine levels and cellular health, Nutravision provides an additional pathway of protection to help safeguard macular health over the long term.

Conclusion: A Smarter Approach to Macular Health

The macula is one of the body’s most intricate and energy-demanding structures. Protecting it effectively over the long term requires more than two carotenoids or a one-size-fits-all formula.

Nutravision, built on the NP-10 System™, combines evidence-based nutrition with clinical insight to support the macula from multiple angles:

• Triple carotenoid protection with lutein, zeaxanthin, and saffron
• Zinc-free design for safer, long-term use
• Five-fold antioxidant power that reaches the mitochondria
• Circulation support for oxygen and nutrient delivery
• And homocysteine metabolism to maintain vascular integrity

Together, these pathways create a stronger foundation for long-term macular health and visual clarity.

For proactive individuals, Nutravision represents a smarter way to care for your eyes; built on science, designed for those who look deeper.